2-Cyanoethyl diisopropylchlorophosphoramidite, 95%, Thermo Scientific Chemicals
Product code L18575 Thermo Scientific
Catalog number ALF-L18575-06
- INR 28,010.00 / EA
Description
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3'-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
Solubility
Miscible with chloroform and dichloromethane.
Notes
Reacts violently with water. Incompatible with alcohols and strong bases.
Specifications
| Density | 1.061 |
| Boiling Point | 103°C to 105°C (0.08 mmHg) |
| Flash Point | >110°C (230°F) |
| Refractive Index | 1.478 |
| Quantity | 5 g |
| UN Number | UN2845 |
| Beilstein | 3588525 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Miscible with chloroform and dichloromethane. |
| Formula Weight | 236.68 |
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Safety and Handling
GHS H Statement
H250-H252-H314-H318-H302
Catches fire spontaneously if exposed to air.
Self-heating in large quantities; may catch fire.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
P210-P222-P260-P264b-P280-P301+P330+P331-P302+P334-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
H250-H314
DOTInformation : Transport Hazard Class: 4.2; Packing Group: I; Proper Shipping Name: PYROPHORIC LIQUIDS, ORGANIC, N.O.S.
TSCA : No
Recommended Storage : Store at -20°C; Store under Argon